This trial has been completed.

Condition type 1 diabetes mellitus
Sponsor Washington University School of Medicine
Start date April 2007
End date December 2013
Trial size 91 participants
Trial identifier NCT00918801, 06-0786


This study is an expansion of a previous study done to determine how thinking skills relate to hypoglycemia (low blood sugar) and certain regions of the brain in children and adolescents. In this study, the investigators are testing thinking skills and measuring brain activity in adolescents with and without type 1 diabetes mellitus.

United States No locations recruiting
Other countries No locations recruiting

Study Design

Observational model case control
Time perspective prospective
Adolescents ages 13-18 with T1DM
Healthy adolescents ages 13-18 without T1DM

Eligibility Criteria

Male or female participants from 13 years up to 18 years old.

Inclusion Criteria: - Age 13 - 18 - Right handed - Diagnosis of Type 1 Diabetes OR normal sibling control - If diabetic, then diagnosis for at least 2 years Exclusion Criteria: - Pregnant or lactating - Chronic disease other than well-controlled asthma, or Hashimoto's thyroiditis. - Other current serious medical illness - Co-morbid psychiatric illness - Co-morbid neurological illness - Pre-maturity at birth - Contraindication to MRI scan - orthodontic braces.

Additional Information

Official title Pilot Study of Hippocampal Function in T1DM
Principal investigator Tamara G Hershey, PhD.
Trial information was received from ClinicalTrials.gov and was last updated in November 2016.
Information provided to ClinicalTrials.gov by Washington University School of Medicine.