Trans Nasal Insuflation for the Treatment of Snoring
This trial is active, not recruiting.
|Condition||obstructive sleep apnea|
|Treatment||trans nasal insuflation (tni) [nasal canula]|
|Sponsor||Johns Hopkins University|
|Start date||July 2004|
|Trial size||100 participants|
|Trial identifier||NCT00832026, NA_00019483|
This research is being done to examine if a nasal cannula can be used to keep the throat open during sleep, thereby treating sleep apnea.
People with sleep apnea and people who snore without sleep apnea may take part in this study. Sleep apnea is a disorder caused by pauses in breathing due to repetitive closure of the throat. The most common form of treatment for sleep apnea is continuous positive airway pressure (CPAP) therapy. While CPAP therapy remains the simplest and most effective treatment for snoring and sleep apnea, patients have to wear a nasal mask throughout the night. For this reason, patients often have difficulty sticking to therapy.
Participants enrolled in this study will spend 3-nights in a sleep laboratory. In all nights, the investigators will monitor your sleep and your breathing throughout the night. The investigators will apply several electrodes (sensors) to your scalp and face to monitor your sleep and breathing, and other sensors to your chest, abdomen, cheek, and a finger to monitor your breathing and oxygen level.
Change in inspiratory airflow
time frame: 2 nights
Change in sleep apnea severity (AHI)
time frame: 2 nights
Change in Ratio of apnea-to-hypopnea events
time frame: 2-nights
Male or female participants at least 21 years old.
Inclusion Criteria: - Consenting adults over the age of 21 - Diagnosed obstructive sleep apnea Exclusion Criteria: - Unstable cardiovascular disease; - Uncontrolled hypertension (BP > 190/110); - Severe intrinsic lung diseases (supplemental O2 > 2 L/min during the day); - History of chronic renal insufficiency; - History of hepatic insufficiency; - Pregnancy; - Bleeding disorders or Coumadin use; - Sleep Disorders other than OSA; - Tracheostomy; - Allergy to lidocaine
|Official title||Trans Nasal Insuflation for the Treatment of Snoring and Obstructive Sleep Apnea|
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