Improving Human Ovarian Transplantation
This trial is active, not recruiting.
|Sponsor||Hadassah Medical Organization|
|Collaborator||Israel Science Foundation|
|Start date||January 2009|
|End date||January 2012|
|Trial size||100 participants|
|Trial identifier||NCT00827476, 0530-08-HMO- CTIL|
we will perform xenotransplantation and in vitro culture of ovarian tissue from patients undergoing ovarian cortex cryopreservation.
|Endpoint classification||efficacy study|
|Intervention model||single group assignment|
tissue will be used for xenotransplantation or in vitro culture
improving folliculogenesis and oocuyte maturation after ovarian transplantation
time frame: 2 years
Female participants from 5 years up to 40 years old.
Inclusion Criteria: - tissue previously obtained Exclusion Criteria: - no tissue available or no consent
|Official title||Phase 1 Study to Improve Results of Human Ovarian Transplantation|
|Description||Ovarian tissue is removed by laparoscopy and only in patients facing premature ovarian failure due to chemotherapy.Tissue for research will consist either of a small portion (<10%) of the cortex for preservation for young women. another source of ovarian tissue for research will be obtained following consent from family of patients who have died of the disease and have previously frozen ovarian tissue.|
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