Overview

This trial is active, not recruiting.

Condition fertility preservation
Treatment ovarian transplantation
Phase phase 0
Sponsor Hadassah Medical Organization
Collaborator Israel Science Foundation
Start date January 2009
End date January 2012
Trial size 100 participants
Trial identifier NCT00827476, 0530-08-HMO- CTIL

Summary

we will perform xenotransplantation and in vitro culture of ovarian tissue from patients undergoing ovarian cortex cryopreservation.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Endpoint classification efficacy study
Intervention model single group assignment
Masking open label
Primary purpose treatment
Arm
(Experimental)
tissue will be used for xenotransplantation or in vitro culture
ovarian transplantation
ovarian xenotransplantation or in vitro culture

Primary Outcomes

Measure
improving folliculogenesis and oocuyte maturation after ovarian transplantation
time frame: 2 years

Eligibility Criteria

Female participants from 5 years up to 40 years old.

Inclusion Criteria: - tissue previously obtained Exclusion Criteria: - no tissue available or no consent

Additional Information

Official title Phase 1 Study to Improve Results of Human Ovarian Transplantation
Description Ovarian tissue is removed by laparoscopy and only in patients facing premature ovarian failure due to chemotherapy.Tissue for research will consist either of a small portion (<10%) of the cortex for preservation for young women. another source of ovarian tissue for research will be obtained following consent from family of patients who have died of the disease and have previously frozen ovarian tissue.
Trial information was received from ClinicalTrials.gov and was last updated in January 2009.
Information provided to ClinicalTrials.gov by Hadassah Medical Organization.