Overview

This trial is active, not recruiting.

Conditions trismus, edema, pain
Treatment etodalac, etoricoxib and dexamethasone
Sponsor Tel-Aviv Sourasky Medical Center
Start date November 2008
End date December 2009
Trial size 80 participants
Trial identifier NCT00793052, TASMC-08-BS-062-CTIL

Summary

The purpose of this study is to determine whether Etodalac, Etoricoxib and Dexamethasone are effective for Prevention of Pain ,Swelling and Trismus Following Third Molar Surgery

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Endpoint classification efficacy study
Intervention model single group assignment
Masking double blind (subject, caregiver, investigator)
Primary purpose treatment
Arm
(Experimental)
etodalac, etoricoxib and dexamethasone
Dexamethasone sodium phosphate 8 mg 1 hour before the extraction, 4 mg the day after the extraction and another 4 mg at second day to the extraction. Etoricoxib 120 mg 1 hour before the extraction, 120 mg the day after the extraction and another 120 mg at second day to the extraction. Etodalac 600 mg 1 hour before the extraction, 600 mg the day after the extraction and another 600 mg at second day to the extraction.

Primary Outcomes

Measure
PAIN- By VAS graded from 1-10 TRISMUS- By MAX mouth opening from the first incisors adages POST OPERATIVE SWELLing - By measurement the distance between the Right and LEFT ear's tragus
time frame: 1 week

Eligibility Criteria

Male or female participants at least 18 years old.

Inclusion Criteria: - Patients who are refered for third molar extraction to our center - Must be able to swallow tablets Exclusion Criteria: - Diabetes mellitus - Thyroid diseases - Cardiovascular diseases - renal diseases - hepatic diseases - respiratory system diseases - adrenal diseases - Allergy to Etodalac, Etoricoxib or Dexamethasone - Gastric ulcers - psychiatric diseases - Pregnant or breast feeding womans

Additional Information

Official title Etodalac, Etoricoxib and Dexamethasone for Prevention of Pain ,Swelling and Trismus Following Third Molar Surgery: A Prospective, Double-Blind Study
Trial information was received from ClinicalTrials.gov and was last updated in November 2008.
Information provided to ClinicalTrials.gov by Tel-Aviv Sourasky Medical Center.