Effect of Treatment With Stress-Doses Glucocorticoid in Patients With Acute Respiratory Distress Syndrome (ARDS)
This trial is active, not recruiting.
|Conditions||acute respiratory distress syndrome, adrenal insufficiency|
|Sponsor||Southeast University, China|
|Collaborator||Nanjing Medical University|
|Start date||December 2008|
|End date||April 2009|
|Trial size||100 participants|
|Trial identifier||NCT00773058, QHB-YY 2008|
The purpose of this study is to see if stress doses of hydrocortisone improve early outcome in patients who are in early stage of ARDS and with relative adrenal insufficiency.
|Endpoint classification||safety/efficacy study|
|Intervention model||parallel assignment|
|Masking||single blind (subject)|
Evidence of clinically definite ARDS confirmed by AECC criteria in 1994
time frame: within the first 3 days after surgery onset of ARDS
Male or female participants from 18 years up to 85 years old.
Inclusion Criteria: - within the first 3 days of onset of clinically definite ARDS confirmed by AECC criteria in 1994 - 18 to 85 year old Exclusion Criteria: - pregnancy or lactation - tumor or other immunologic disease - immunosuppressive drug used - bone marrow or lung transplantation - primary or secondary disease of adrenal gland - hormone used within 3 months - refusing conventional therapy - be in other clinical tests within 30 days
|Official title||Effect of Treatment With Stress-Doses Glucocorticoid on Mortality in Patients With ARDS and Relative Adrenal Insufficiency|
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