This trial is active, not recruiting.

Condition pulmonary arteriovenous malformations
Sponsor Imperial College London
Trial size 45 participants
Trial identifier NCT00733759, IC/CLS10


Pulmonary arteriovenous malformations (PAVMs) are thin-walled abnormal vessels which provide direct capillary-free communications between the pulmonary and systemic circulations. Patients with PAVMs have usually have low blood oxygen levels and are at risk of other complications including strokes, brain abscesses, pregnancy-related complications and haemorrhage. We hypothesise that the complications of PAVM patients arise from their PAVMs and not the more recognised intracardiac forms of shunting. We propose to perform echocardiograms to enable assessment of the presence of other causes of capillary-free communications between the pulmonary and systemic circulations.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Time perspective prospective

Eligibility Criteria

Male or female participants of any age.

Inclusion Criteria: - patients with pulmonary arteriovenous malformations (PAVMs) Exclusion Criteria: - unable to provide informed consent

Additional Information

Official title The Evaluation of Intra-Cardiac Shunts in Patients With Pulmonary Arteriovenous Malformations
Principal investigator Claire L Shovlin
Trial information was received from ClinicalTrials.gov and was last updated in August 2008.
Information provided to ClinicalTrials.gov by Imperial College London.