Contrast Echocardiography in Patients With Pulmonary Arteriovenous Malformations (PAVMs)
This trial is active, not recruiting.
|Condition||pulmonary arteriovenous malformations|
|Sponsor||Imperial College London|
|Trial size||45 participants|
|Trial identifier||NCT00733759, IC/CLS10|
Pulmonary arteriovenous malformations (PAVMs) are thin-walled abnormal vessels which provide direct capillary-free communications between the pulmonary and systemic circulations. Patients with PAVMs have usually have low blood oxygen levels and are at risk of other complications including strokes, brain abscesses, pregnancy-related complications and haemorrhage. We hypothesise that the complications of PAVM patients arise from their PAVMs and not the more recognised intracardiac forms of shunting. We propose to perform echocardiograms to enable assessment of the presence of other causes of capillary-free communications between the pulmonary and systemic circulations.
Male or female participants of any age.
Inclusion Criteria: - patients with pulmonary arteriovenous malformations (PAVMs) Exclusion Criteria: - unable to provide informed consent
|Official title||The Evaluation of Intra-Cardiac Shunts in Patients With Pulmonary Arteriovenous Malformations|
|Principal investigator||Claire L Shovlin|
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