This trial is active, not recruiting.

Condition appendicitis
Treatment mri of the abdomen
Sponsor Children's Research Institute
Start date August 2008
End date March 2012
Trial size 120 participants
Trial identifier NCT00723788, CNMC4024


Study to find out if MRI can diagnose appendicitis in children as well as or better than CT scan and/or ultrasound scan performed at the same time. No additional contrast material or sedation will be used to perform the MRI.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Endpoint classification safety/efficacy study
Intervention model single group assignment
Masking single blind (investigator)
Primary purpose diagnostic
All patients enrolled will receive an MRI of the abdomen with detailed views of the appendix
mri of the abdomen
Multiple MRI pulse sequences of the abdomen

Primary Outcomes

Diagnostic Sensitivity, specificity and accuracy of appendiceal MRI compared to ultrasound, CT scan, and gold standard of either surgical findings or clinical follow-up
time frame: 6 weeks after scans obtained

Secondary Outcomes

Duration of MRI scan and effect on emergency department disposition of potential patients with appendicitis
time frame: At time of scan
Cost-effectiveness of appendiceal MRI compared to CT scan or ultrasound
time frame: At time of scan

Eligibility Criteria

Male or female participants from 8 years up to 18 years old.

Inclusion Criteria: - Age 8-18 years, referred from emergency department for suspected appendicitis and receiving either CT scan or ultrasound of the abdomen for diagnosis Exclusion Criteria: - Failure to pass MRI metal screening. Claustrophobia or need for sedation due to inability to hold still.

Additional Information

Official title Magnetic Resonance Evaluation of Appendicitis in Children Aged 8-18
Principal investigator Pranav K Vyas, MD
Trial information was received from ClinicalTrials.gov and was last updated in June 2011.
Information provided to ClinicalTrials.gov by Children's Research Institute.