This trial is active, not recruiting.

Condition cannabis use disorders
Treatment cognitive-behavioral treatment
Phase phase 3
Sponsor Technische Universität Dresden
Collaborator Federal Ministry of Health
Start date May 2008
End date October 2009
Trial size 450 participants
Trial identifier NCT00673647, IIA5-2507DSM407


The purpose of this study is to evaluate the effectiveness of the cognitive-behavioral treatment program CANDIS among n=450 patients with cannabis use disorders in a mulicenter randomized-controlled clinical trial (n=11 outpatient treatment centers).

United States No locations recruiting
Other countries No locations recruiting

Study Design

Allocation randomized
Endpoint classification efficacy study
Intervention model crossover assignment
Masking open label
Primary purpose treatment
Individual psychotherapy including cognitive behavioral components, motivational interviewing techniques and case management
cognitive-behavioral treatment delayed treatment control group
10 sessions of individual psychotherapy including cognitive-behavioral treatment, motivational enhancement and a psychosocial problem training.
(No Intervention)
Delayed treatment control group

Primary Outcomes

abstinence, defined as no evidence of cannabis use during the past 4 weeks as evidenced by self report and a negative urine screen; number of times a cannabis product was used in the past 4 weeks; retention rate
time frame: at the end of treatment

Eligibility Criteria

Male or female participants at least 16 years old.

Inclusion Criteria: - motivation to change cannabis use - age 16 or older - current (12 mth) regular cannabis use (at least 2 days a week) - informed consent to the study procedures and assessments Exclusion Criteria: - current alcohol or any illicit drug dependence syndrome according to DSM-IV other than due to cannabis - lifetime history of any psychotic disorder - current severe episode of Major depression - current panic-agoraphobic disorder (severe) - severe learning disability, brain damage or pervasive developmental disorder - currently acute suicidality - not fluent in german language - any other current treatment for cannabis use disorders

Additional Information

Official title Evaluation of the Cognitive-behavioral Treatment Programme CANDIS in the German Outpatient Treatment Service System (CANDIS-II)
Principal investigator Eva Hoch, PhD
Trial information was received from ClinicalTrials.gov and was last updated in August 2009.
Information provided to ClinicalTrials.gov by Technische Universität Dresden.