Multicenter Myocardial Viability Trial
This trial is active, not recruiting.
|Condition||coronary artery disease|
|Sponsor||St. Luke's Medical Center, Texas|
|Start date||August 2003|
|End date||October 2008|
|Trial size||235 participants|
|Trial identifier||NCT00661232, 1102-02-777, IND# 66,506, NDA# 20-937|
The purpose of this study is to test the hypothesis of whether contrast enhanced Magnetic Resonance Imaging can be used to predict improvement of the wall motion in regions of the heart with abnormal movement following bypass surgery or percutaneous angioplasty in various institutions across three continents.
|United States||No locations recruiting|
|Other Countries||No locations recruiting|
|Houston, TX||St. Luke's Episcopal Hospital||no longer recruiting|
|Houston, TX||St. Luke's Episcopal Location||no longer recruiting|
|Brussels, Belgium||Cliniques Universitaires St. Luc||no longer recruiting|
|Aarhus N, Denmark||Skejby University Hospital||no longer recruiting|
|Maroussi, Greece||Hygeia Hospital||no longer recruiting|
|Bangkoknoi, Thailand||Siriraj Hospital||no longer recruiting|
|Leeds, United Kingdom||Cardiac MRI Unit||no longer recruiting|
To examine whether the extent of irreversible myocardial injury as assessed by Delayed Enhancement Magnetic Resonance Imaging can predict the extent of functional recovery after revascularization in patients with chronic coronary artery disease (CAD).
time frame: 36 months
Male or female participants from 21 years up to 85 years old.
Inclusion Criteria: - Age: > 21 years and < 85 years - Sinus rhythm - Weight < 120 kg - LVEF > 30% - Wall motion abnormality on Echo. or LV-gram - Scheduled for revascularization - Angioplasty/Stent or CABG - within 30 days Exclusion Criteria: - Resting heart rate > 100 bpm - Frequent atrial or ventricular ectopy - Severe aortic stenosis or HOCM - Unstable angina - Myocardial infarction within 14 days - Active congestive heart failure - Pregnancy - Known allergy to gadolinium - Contraindication to MRI
|Official title||An International, Multicenter Trial Assessing Myocardial Viability With Contrast - Enhanced Magnetic Resonance Imaging|
|Principal investigator||Scott D Flamm, M.D.|
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