The Role of Central Serotonergic and Adrenergic Systems in the Effectiveness of DNIC (Diffuse Noxious Inhibitory Control
This trial is active, not recruiting.
|Sponsor||Rambam Health Care Campus|
|Start date||August 2007|
|End date||August 2009|
|Trial size||100 participants|
|Trial identifier||NCT00660751, DNIC01CTIL|
The role of central serotonergic and adrenergic systems in the effectiveness of DNIC (Diffuse Noxious Inhibitory Control) will be tested before and after taking Duloxetine and Placebo in a double blind study.
|Intervention model||single group assignment|
|Masking||double blind (subject, investigator, outcomes assessor)|
|Primary purpose||basic science|
level of DNIC
time frame: 1 week
Male or female participants from 18 years up to 80 years old.
- Healthy volunteers
- age 18-80
- no chronic disease
- Subjects who suffer from chronic pain / pain syndrome
- use of anti-depressant or anti-psychotic drugs
- food/ drugs sensitivity
- breast feeding
|Official title||The Role of Central Serotonergic and Adrenergic Systems in the Effectiveness of DNIC (Diffuse Noxious Inhibitory Control|
|Principal investigator||Prof. David Yarnitsky|
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