The Effect of Intravenous Lidocaine on Allodynia
This trial is active, not recruiting.
|Sponsor||University of Alabama at Birmingham|
|Collaborator||American Society of Regional Anesthesia|
|Start date||December 2008|
|End date||June 2016|
|Trial size||10 participants|
|Trial identifier||NCT00659633, F061204014|
The purpose of this study is to study if lidocaine, given intravenously, reduces pain.
|Endpoint classification||efficacy study|
|Intervention model||single group assignment|
Intravenous lidocaine for neuropathic pain
time frame: before, during, and after intravenous lidocaine
Male or female participants at least 19 years old.
Inclusion Criteria: - Chronic Regional Pain Syndrome diagnostic criteria by the Work Safe BC. vi Exclusion Criteria: - History of Substance abuse - Other Medications: CRPS patients are expected to be treated for chronic pain, whether the current treatment regimen interferes with sensory motor testing will be determined on a case by case basis. - Coronary Artery Disease (CAD): unstable - Congestive Heart Failure (CHF): unstable - Heart Arrhythmia: symptomatic - Chronic Obstructive Pulmonary Disease (COPD) - Lidocaine Allergy - Diagnostic and Statistical Manual of Mental Disorders (Rev IV): Axis I: Common Axis I disorders include depression, anxiety disorders, bipolar disorder, ADHD, and schizophrenia. Axis II: borderline personality disorder, schizotypal personality disorder, antisocial personality disorder, and mild mental retardation. - Presence of Contraindications for MRI - Presence of electronically, magnetically, and mechanically activated implants - Electronically, magnetically, and mechanically activated implants - Ferromagnetic or electronically operated active devices like automatic cardioverter defibrillators - Cardiac pacemakers - Metallic splinters in the eye - Ferromagnetic haemostatic clips in the central nervous system (CNS) - Claustrophobia - Pregnancy
|Official title||The Effect of Intravenous Lidocaine on Allodynia (Carl Koller Grant)|
|Principal investigator||Michael Froelich, MD, MS|
|Description||Clinicians use lidocaine intravenously in a fashion that suggests that it might have analgesic effects. Therefore, we test the hypothesis that lidocaine reduces pain intensity in response to experimental pain.|
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