Aortic Dimensions in Turner Syndrome
This trial is active, not recruiting.
|Sponsor||University of Aarhus|
|Start date||August 2003|
|End date||June 2012|
|Trial size||102 participants|
|Trial identifier||NCT00624949, 20010248|
An observational study of 102 women with Turner syndrome followed for 6 years with a two-yearly examination including ECHO, MRI of the heart and 24 ambulatory blood pressure. It has been found that besides an significantly increased risk of congenital cardiac malformations, TS have an increased risk of developing cardiac disease including the life threatening condition of aortic dilatation and rupture. The aim of the study is to describe the cardiac conditions of TS, evaluate different methods of examination and identify possible risc factors.
women with Turner syndrome
Aortic diameter at 3 well-defined levels measured by MRI and ECHO
time frame: 2-yearly for 6 years
24hour ambulatory blood pressure
time frame: 24h 2-yearly for 6 years
Female participants from 18 years up to 70 years old.
Inclusion Criteria: - Turner syndrome - Age 18-70 years Exclusion Criteria: - Extreme adipositas - Contraindications to a MRI scan - Malignant disease
|Official title||Aortic Dimensions, 24hour Ambulatory Blood Pressure and Sympathovagal Tone in Turner Syndrome. In Relation to Aortic Dilatation and Dissection.|
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