This trial is active, not recruiting.

Conditions galactosemia, premature ovarian failure
Treatment follitropin and lutropin
Sponsor Maastricht University Medical Center
Collaborator Galactosemie Vereniging Nederland (The Dutch Galactosemia Society)
Start date March 2007
End date March 2010
Trial size 25 participants
Trial identifier NCT00619333, MEC 06-2-073


The aim of the study is to investigate whether inactive FSH plays a role in the development of Premature Ovarian Failure in women with Classic Galactosemia

United States No locations recruiting
Other countries No locations recruiting

Study Design

Intervention model single group assignment
Masking open label
follitropin and lutropin
follitropin and lutropin

Primary Outcomes

Estradiol response
time frame: 3 days

Eligibility Criteria

Female participants at least 18 years old.

Inclusion Criteria: - Diagnosis of galactosemia through GALT-activity analysis and/or mutation analysis - Premature Ovarian Failure with FSH > 30 U/l Exclusion Criteria: - Gynecological cancers and/or unexplained vaginal bleeding

Additional Information

Official title The Role of Inactive Follicle Stimulating Hormone in Ovarian Dysfunction in Galactosemia
Principal investigator Estela Rubio-Gozalbo, MD, PhD
Trial information was received from ClinicalTrials.gov and was last updated in January 2010.
Information provided to ClinicalTrials.gov by Maastricht University Medical Center.