Overview

This trial is active, not recruiting.

Condition ptsd
Treatments cognitive processing therapy, present centered therapy
Sponsor VA Office of Research and Development
Start date June 2009
End date February 2015
Trial size 79 participants
Trial identifier NCT00607815, MHBA-007-07F

Summary

The purpose of this study is to compare the effectiveness of Cognitive Processing Therapy (CPT) versus Present Centered Therapy (PCT) for male OEF/OIF Veterans with combat related PTSD.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Allocation randomized
Endpoint classification efficacy study
Intervention model parallel assignment
Masking double blind (investigator, outcomes assessor)
Primary purpose treatment
Arm
(Active Comparator)
Cognitive Processing Therapy
cognitive processing therapy
CPT is a highly structured protocol in which the client learns the skill of recognizing and challenging dysfunctional cognitions, first about the worst traumatic event and then later with regard to the meaning of the events for current beliefs about self and others.
(Active Comparator)
Present Centered Therapy
present centered therapy
Present centered therapy is a supportive counseling model developed by Drs. Foa and Shea. The treatment is called "present centered therapy" to 1) emphasize the need to focus on the participant's current life and 2) to conceptualize the problems as being caused by PTSD, and in some cases they may have been present for a long period of time. The treatment makes a connection between PTSD and current problems thus making it a more realistic PTSD treatment and still allowing PCT to control for nonspecific therapeutic factors

Primary Outcomes

Measure
Clinician Administered PTSD Scale
time frame: Post-treatment, at 3 months and 1 year
PTSD Checklist (PCL)
time frame: post-treatment, at 3 months and 1 year

Secondary Outcomes

Measure
Beck Depression Inventory - II (BDI-II)
time frame: post-treatment, at 3 months and 1 year
State-Trait Anger Scale (STAXI)
time frame: post-treatment, at 3 months and 1 year
State-Trait Anxiety Scale
time frame: post-treatment, at 3 months and 1 year

Eligibility Criteria

Male participants from 18 years up to 75 years old.

Inclusion Criteria: - PTSD; - memory of the trauma; - able to read/write; - must be stable on medication for 3 months Exclusion Criteria: - Psychosis; - suicidal/homicidal intent; - alcohol/substance dependence; - no memory of the trauma

Additional Information

Official title A Comparison of CPT vs PCT for Veterans
Principal investigator Kathleen M Chard, PhD
Description The purpose of this study is to compare the effectiveness of Cognitive Processing Therapy (CPT) versus Present Centered Therapy (PCT) for male OEF/OIF Veterans with combat related PTSD. CPT has been shown to be effective in treating trauma survivors in several treatment outcome studies, but utility with Veterans has only been examined with male Veterans in one small pilot study. In addition CPT has never been compared to a treatment as usual or supportive psychotherapy condition to control for the specific and nonspecific elements of treatment. Although Cognitive Processing Therapy is one of the main treatment modalities at several VA's, including Cincinnati, it has never been compared to PCT, nor has it been used in a large, randomized study of male OEF/OIF Veterans. It is hypothesized that individual receiving CPT will show a larger reduction in posttraumatic stress disorder and related symptoms than those individuals receiving PCT. All male OEF/OIF Veterans will be screened for their appropriateness for the study by phone screen and then by an assessment technician. The Veteran will be assessed at pre, post, 3-month, and 1-year follow-up. The assessment technicians will be blind to the participant's condition. CPT is a 12 week long individual psychotherapy treatment shown to be effective at reducing PTSD and related symptoms for survivors of various types of traumas, including combat. PCT is a supportive counseling treatment that has been utilized as an alternative to waitlist control in VA cooperative studies of PTSD.
Trial information was received from ClinicalTrials.gov and was last updated in February 2016.
Information provided to ClinicalTrials.gov by VA Office of Research and Development.