Impact of Diet and/or Exercise-Induced Weight Loss on Cardiovascular Risk Factors
This trial is active, not recruiting.
|Treatment||diet and/or exercise|
|Start date||August 2003|
|End date||February 2007|
|Trial size||30 participants|
|Trial identifier||NCT00588978, 25094|
The purpose of this pilot study is to examine the effect of diet and/or exercise-induced weight loss on nontraditional cardiovascular risk factors such as c-reactive protein, insulin levels and sex steroids in obese postmenopausal women.
|Endpoint classification||safety/efficacy study|
|Intervention model||parallel assignment|
time frame: baseline, every 1-2 weeks during intervention , then end-of-study
HOMA (measure of insulin resistance) and sex steroids
time frame: baseline, every 1-2 weeks during intervention, then end-of-study
Female participants from 40 years up to 65 years old.
Inclusion Criteria: - obese postmenopausal women - able to exercise - non-smokers Exclusion Criteria: - cardiovascular disease - medications that would interfere with outcome measures (e.g., including ACE inhibitors, lipid lowering medications, beta-blockers, etc) - known diabetes
|Official title||Longitudinal Impact of Diet and/or Exercise-Induced Weight Loss on Metabolic Markers of Cardiovascular Disease|
|Principal investigator||Barbara I Gulanski, MD, MPH|
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