This trial is active, not recruiting.

Condition schizophrenia
Treatments social cognition interaction training, wlc
Phase phase 2/phase 3
Sponsor VA Connecticut Healthcare System
Start date January 2008
End date December 2013
Trial size 75 participants
Trial identifier NCT00587561, D4628W, JMF0005


The term social cognition refers to how social information is processed. Individuals with schizophrenia and schizoaffective disorder have been shown to have significant deficits in social cognition. Moreover, it has been speculated that these deficits may in turn have a negative impact on their overall functioning. Behavioral interventions targeting social cognition are just beginning to emerge, and there is a need to evaluate their efficacy.


This is a small trial evaluating the efficacy of social cognition interaction training (SCIT) an experimental behavioral treatment for improving social cognition in schizophrenia.

Research Design and Methodology:

Approximately 48 participants with schizophrenia-spectrum disorders will be randomized into one of two conditions: 1) a 20 to 24 session manualized social cognition interaction training group (SCIT), or 2) wait-list control. Pre-and post-group therapy assessments of symptoms, social cognition, basic cognition, and community function will be conducted. Data obtained from this study will allow us to determine the efficacy of SCIT training in improving symptom, cognitive, and functional measures.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Allocation randomized
Endpoint classification efficacy study
Intervention model crossover assignment
Masking open label
Primary purpose treatment
Will receive 20-26 sessions of a manualized group treatment called Social Cognition Interaction Training
social cognition interaction training
manualized group therapy
Wait list control; 6 months of treatment as usual followed by Social Cognition Interaction Training group
wait-list control for 6 months, followed by the experimental group therapy

Primary Outcomes

Social cognitive measures
time frame: intake, 6 months, 9 months

Secondary Outcomes

basic cognitive measures
time frame: intake, 6 months, 9 months

Eligibility Criteria

Male or female participants from 18 years up to 65 years old.

Inclusion Criteria: - diagnosis of schizophrenia or schizoaffective disorder - Age between 18 and 65 - minimum of 30 days since discharge from last hospitalization - minimum of 30 days since last change in psychiatric medications - no housing changes in the past 30 days Exclusion Criteria: - current diagnosis of alcohol or substance abuse/dependence - history of brain trauma or neurological disease - mental retardation or developmental disability - auditory or visual impairment that would interfere with study procedures

Additional Information

Official title Efficacy of Social Cognition Training in Schizophrenia
Principal investigator Joanna Fiszdon, Ph.D.
Trial information was received from ClinicalTrials.gov and was last updated in June 2015.
Information provided to ClinicalTrials.gov by VA Connecticut Healthcare System.