Oral Water Ingestion in Heart Transplant Patients
This trial is active, not recruiting.
|Conditions||blood pressure, cardiac transplantation|
|Sponsor||Satish R. Raj|
|Collaborator||National Center for Research Resources (NCRR)|
|Start date||January 2006|
|End date||December 2017|
|Trial size||40 participants|
|Trial identifier||NCT00581321, 050811, UL1RR024975|
In this study the investigators propose to assess the hemodynamic response to the ingestion of 16 fl oz of water. The investigators will test the hypothesis that water ingestion will increase the systemic vascular resistance.
|United States||No locations recruiting|
|Other countries||No locations recruiting|
|Intervention model||single group assignment|
change in total vascular resistance
time frame: 40 min (before to 30 min after water ingestion
time frame: 40 min
time frame: 40 min
time frame: 40 minutes
All participants at least 18 years old.
Inclusion Criteria: - s/p cardiac transplantation scheduled for clinical right heart catheterization - age > 18 years Exclusion Criteria: - significant tricuspid regurgitation - inability to safely swallow 500 ml of water - other major medical comorbidities such as advanced renal disease where water ingestion may be harmful to patient
|Official title||Acute Hemodynamic Effects of Oral Water in a Stable Cardiac Transplant Population|
|Principal investigator||Satish R Raj, MD, MSCI|
|Description||In this study we propose to assess the hemodynamic response to the ingestion of 16 fl oz of water. We will test the hypothesis that water ingestion will increase the systemic vascular resistance. This study will occur in patients status post cardiac transplantation during their clinical right heart catheterizations. Invasive hemodynamics including cardiac outputs and plasma norepinephrine levels will be measured before and 30 min after the water ingestion.|
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