This trial is active, not recruiting.

Conditions breast cancer, prostate cancer
Sponsor Memorial Sloan Kettering Cancer Center
Collaborator City of Hope National Medical Center
Start date September 2006
End date December 2017
Trial size 201 participants
Trial identifier NCT00580476, 06-100


The goal of this study is to learn more about how we measure depression in elderly cancer patients (patients aged 70 and older). Depression is one of the most common causes of emotional distress in the elderly and continues to be under-recognized. This is a problem because depression can have a negative impact on quality of life. The symptoms of depression are linked to poor health outcomes and higher costs of health care. In fact, depression is one of the top five concerns facing the elderly today.

United States No locations recruiting
Other countries No locations recruiting

Study Design

Observational model case-only
Time perspective prospective
150 patients will be women with breast cancer (75 early stage and 75 late stage)
150 will be men with prostate cancer (75 early stage and 75 late stage)

Primary Outcomes

Test the sensitivity and specificity of the Geriatric Depression Scale-Short Form and two other widely used assessments of depression to detect major and minor depression in a geriatric breast and prostate cancer population.
time frame: 2 years

Secondary Outcomes

To develop a cut-off score for the GDS that is specific to a cancer population.
time frame: 2 years

Eligibility Criteria

Male or female participants at least 70 years old.

Inclusion Criteria: 1. Age 70 and older 2. Diagnosis of early or late stage prostate cancer, or diagnosis of early or late stage breast cancer 3. Actively engaged in one of the following cancer treatments: chemotherapy, radiation therapy, hormone therapy 4. Able to provide informed consent 5. Ability to converse, write and read English Exclusion Criteria: 1.Major psychopathology or cognitive impairment likely in the judgment of the research staff to interfere with the participation or completion of the protocol.

Additional Information

Official title Assessing Depression in a Geriatric Cancer Population
Principal investigator Christian Nelson, Ph.D.
Description We have a few questionnaires that have been used to measure depression, but we do not know how these measures work with people with cancer. This study will help us answer this question. To complete this study, we need people who may or may not be feeling down or depressed. If you choose to take part, you will be asked to do the following: 1. Fill out questionnaires that ask about: - Your age, eduction, race, and income - Your mood In all, these questionnaires will take about 10 minutes to complete. 2. Answer questions about your mood. This will also take about 10 minutes to complete.
Trial information was received from ClinicalTrials.gov and was last updated in December 2016.
Information provided to ClinicalTrials.gov by Memorial Sloan Kettering Cancer Center.