Overview

This trial is active, not recruiting.

Condition ptsd
Treatment net
Sponsor University of Konstanz
Collaborator German Research Foundation
Start date January 2007
End date December 2008
Trial size 30 participants
Trial identifier NCT00563888, SOSS-B6

Summary

Effective Treatment of PTSD involves talking about the traumatic event in detail.It is unclear how this process influences the sensory-specific trauma network (fear structure)in the traumatized person. The goal of the project is to test the hypothesis that treatment-facilitated recovery does not change the original fear structure but establishes an inhibitory mechanism that depends on verbal activity. An affective visual steady-state paradigm in magnetencephalography (MEG) using positive, aversive and neutral picture stimuli will be used to examine the spatial and temporal pattern of the processing of emotional stimuli. To examine the effects of treatment this paradigm will be used as outcome measure within a randomized controlled trial of Narrative Exposure Therapy and a waiting-list control condition for severely traumatized torture victims.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Allocation randomized
Intervention model parallel assignment
Masking single blind (outcomes assessor)
Primary purpose treatment
Arm
(Experimental)
Narrative Exposure Therapy (NET)
net
Narrative Exposure Therapy for traumatized survivors of organized violence
(No Intervention)
Waitinglist Control Group

Primary Outcomes

Measure
PTSD diagnosis and severity score according to the Clinicians Administered PTSD Scale (CAPS)
time frame: 4 & 9 months after completion of treatment

Secondary Outcomes

Measure
steady state visual evoked magnetic fields in response to affective stimuli
time frame: 4 & 9 months after completion of treatment

Eligibility Criteria

Male or female participants from 18 years up to 65 years old.

Inclusion Criteria: - experiences of organized violence/torture - PTSD diagnosis Exclusion Criteria: - psychotic disorder - neurological disease or seizures - current drug/alcohol abuse

Additional Information

Official title Change of Neural Network Indicators Through Narrative Treatment of PTSD in Torture Victims
Principal investigator Frank Neuner, Prof.
Trial information was received from ClinicalTrials.gov and was last updated in November 2007.
Information provided to ClinicalTrials.gov by University of Konstanz.