The Active After Cancer Trial (AACT)
This trial is active, not recruiting.
|Conditions||breast cancer, colorectal cancer|
|Treatment||telephone-based exercise intervention|
|Sponsor||Dana-Farber Cancer Institute|
|Collaborator||Cancer and Leukemia Group B|
|Start date||October 2007|
|End date||March 2010|
|Trial size||120 participants|
|Trial identifier||NCT00548236, 07-266|
This study is being done to determine whether a telephone-based counseling intervention can help survivors of breast and colorectal cancer increase their weekly physical activity. Observational evidence suggests that physical activity after breast and colorectal cancer diagnosis decreases recurrence rates. Unfortunately, many people become less active during cancer therapy, and a substantial proportion never return to pre-diagnosis levels of physical activity. This study looks to see if people who have recently finished chemotherapy for breast, colon or rectal cancer can be motivated to increase their exercise by talking to an exercise specialist over the phone. The study also looks at changes in mood, fatigue, fitness, fat distribution and weight.
|United States||No locations recruiting|
|Other countries||No locations recruiting|
|LA Jolla, CA||University of California at San Diego||no longer recruiting|
|San Francisco, CA||University of California San Francisco||no longer recruiting|
|Boston, MA||Dana-Farber Cancer Institute||no longer recruiting|
|Concord, NH||New Hampshire Oncology Hematology||no longer recruiting|
|Hooksett, NH||Lakes Regional Healthcare Hematology Oncology||no longer recruiting|
|Buffalo, NY||Rosewell Park Cancer Institute||no longer recruiting|
|East Syracuse, NY||Hematology Oncology Associates of Central New York||no longer recruiting|
|Columbus, OH||Ohio State University||no longer recruiting|
|Burlington, VT||Vermont Cancer Center||no longer recruiting|
|Endpoint classification||efficacy study|
|Intervention model||parallel assignment|
|Primary purpose||supportive care|
To evaluate the ability of a multi-center, telephone-based physical activity intervention to increase weekly physical activity levels in sedentary patients treated with adjuvant chemotherapy for Stage I-III breast or colorectal cancer.
time frame: months
To evaluate the impact of a physical activity intervention upon fitness, exercise self-efficacy, anthropometric measures, and quality of life in a group of patients with stage I-III breast or colorectal cancer.
time frame: months
Male or female participants at least 18 years old.
Inclusion Criteria: - Histologically confirmed stage I-III breast or colorectal cancer - 18 years of age or older - Completed adjuvant treatment(for current malignancy) - Completion of all adjuvant chemotherapy and radiation (with the exception of adjuvant herceptin and/or tamoxifen/aromatase inhibitor therapy for breast cancer patients) between 2 and 36 months prior to enrollment - Ability to speak and read English - Willingness to be randomized - Medical clearance from an oncologist or primary care physician stating the participant is able to participate in an unsupervised, moderate-intensity physical activity program - No major surgery within 2 months of study enrollment or planned during study period Exclusion Criteria: - Metastatic cancer - Uncontrolled intercurrent illness including, but not limited to, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness that would limit compliance with study requirements - Plans to have hip or knee replacement within a year - Participation in more than 60 minutes a week of moderate-intensity recreational activity as assessed by the International Physical Activity Questionnaire Short Form - BMI >47
|Official title||Pilot Study of a Multicenter, Telephone-Based Exercise Intervention for Patients With Early-Stage Breast and Colorectal Cancer: The Active After Cancer Trial (AACT)|
|Principal investigator||Jennifer Ligibel, MD|
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