Preoperative Hepatic Arterial Infusion Chemotherapy
This trial is active, not recruiting.
|Condition||colorectal liver metastases|
|Sponsor||IRCCS San Raffaele|
|Start date||December 1995|
|Trial identifier||NCT00522509, Neoadjuvant HAIC|
To assess the feasibility and results of liver resection after preoperative hepatic artery infusion (HAI) chemotherapy with FUDR.
|Observational model||defined population|
Male or female participants from 18 years up to 90 years old.
- Unresectable liver metastases
- Potentially resectable liver metastases
- Extrahepatic disease
|Official title||Preoperative Hepatic Arterial Infusion Chemotherapy in Patients Undergoing Liver Resection for Colorectal Liver Metastases|
|Principal investigator||Luca Aldrighetti, M.D, PhD|
|Description||Between 1995 and 2004, 239 patients with isolated colorectal liver metastases received HAI chemotherapy with neoadjuvant intent. Fifty of these patients underwent subsequent curative liver resection (HAI group). Postoperative morbidity, liver function tests, and long term outcomes were evaluated. Adverse events related to HAI chemotherapy were also evaluated.|
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