Overview

This trial is active, not recruiting.

Condition colorectal liver metastases
Treatment floxuridine fudr
Sponsor IRCCS San Raffaele
Start date December 1995
Trial identifier NCT00522509, Neoadjuvant HAIC

Summary

To assess the feasibility and results of liver resection after preoperative hepatic artery infusion (HAI) chemotherapy with FUDR.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Observational model defined population
Time perspective longitudinal

Eligibility Criteria

Male or female participants from 18 years up to 90 years old.

Inclusion Criteria: - Unresectable liver metastases - Potentially resectable liver metastases Exclusion Criteria: - Extrahepatic disease

Additional Information

Official title Preoperative Hepatic Arterial Infusion Chemotherapy in Patients Undergoing Liver Resection for Colorectal Liver Metastases
Principal investigator Luca Aldrighetti, M.D, PhD
Description Between 1995 and 2004, 239 patients with isolated colorectal liver metastases received HAI chemotherapy with neoadjuvant intent. Fifty of these patients underwent subsequent curative liver resection (HAI group). Postoperative morbidity, liver function tests, and long term outcomes were evaluated. Adverse events related to HAI chemotherapy were also evaluated.
Trial information was received from ClinicalTrials.gov and was last updated in August 2007.
Information provided to ClinicalTrials.gov by IRCCS San Raffaele.