What is the Best Preparation for Embryo Transfer in Cryo Cycles: a Natural Cycle or Light Hormonal Stimulation?
This trial is active, not recruiting.
|Treatment||human menopausal gonadotrophins|
|Sponsor||University Hospital, Gasthuisberg|
|Start date||January 2004|
|End date||October 2013|
|Trial size||300 participants|
|Trial identifier||NCT00492934, ML2436 - 30/12/2003|
The study investigates if, among women with a regular cycle (between 25 and 45 days), the endometrium is better prepared for the transfer of an embryo that was cryopreserved and if the subsequent embryo implantation rate is higher when the cycle is started with daily, small-dose hormonal injections than in cycles without these daily injections.
|Endpoint classification||efficacy study|
|Intervention model||parallel assignment|
implantation rate per embryo
time frame: 15 days after the embryo transfer
thickness of the endometrium
time frame: 0-2 days before the human chorionic gonadotropin (hCG) injection
Female participants from 21 years up to 45 years old.
Inclusion Criteria: - Signed informed consent. - Women with a regular cycle (between 21 and 35 days). - Embryos with 50% intact blastomeres after thawing. - Embryo and endometrium are synchronized. Exclusion Criteria: - Embryo storage time not longer than 5 years.
|Official title||Natural Cycle Versus Stimulation With Human Menopausal Gonadotropin in Cycles With Cryopreserved Embryos|
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