This trial is active, not recruiting.

Condition healthy
Treatment salt supplementation
Sponsor Hospital de Clinicas de Porto Alegre
Start date June 2004
End date June 2007
Trial size 20 participants
Trial identifier NCT00465946, HCPA04-071


Syncope is a syndrome consisting of a relatively short period of temporary and self-limited loss of consciousness caused by transient diminution of blood flow to the brain (most often the result of systemic hypotension). The objective of this study was to evaluate the effect of salt supplementation in vasovagal syncope prophylaxis.

United States No locations recruiting
Other countries No locations recruiting

Study Design

Allocation randomized
Endpoint classification efficacy study
Intervention model crossover assignment
Masking double-blind
Primary purpose prevention

Primary Outcomes

Evaluate the effectiveness of the salt supplementation in the prophylaxis of the vasovagal syncope
time frame:

Secondary Outcomes

Evaluate the supplementation salt increases the orthostatic tolerance
time frame:
Analyze the supplementation salt increases the plasmatic volume
time frame:

Eligibility Criteria

Male or female participants from 18 years up to 40 years old.

Inclusion Criteria: - Healthy volunteers Exclusion Criteria: - Use medicines - Previous diseases - Incapacity of to understand and to sign the term consent

Additional Information

Official title Effect of Dietary Salt Supplemantation in Vasovagal Syncope Prophylaxis: A Clinical Trial
Principal investigator Leandro I Zimerman, MD
Description Healthy volunteers without use of medicines with except contraceptives orals that met the exclusion criteria were consecutively enrolled in a randomized trial.
Trial information was received from ClinicalTrials.gov and was last updated in April 2007.
Information provided to ClinicalTrials.gov by Hospital de Clinicas de Porto Alegre.