Overview

This trial is active, not recruiting.

Conditions multiple sclerosis, transverse myelitis, neuromyelitis optica, acute disseminated encephalomyelitis, optic neuritis
Sponsor Accelerated Cure Project for Multiple Sclerosis
Start date May 2006
End date October 2026
Trial size 3226 participants
Trial identifier NCT00445367, ACP-001

Summary

To establish a large, longitudinal collection of high quality samples and data from subjects with MS, selected other demyelinating diseases (Transverse Myelitis (TM), Neuromyelitis Optica (NMO) or Devic's, Acute Disseminated Encephalomyelitis (ADEM), and Optic Neuritis (ON)), and related and unrelated unaffected controls. Samples and data will be available as a shared resource to scientists researching the causes, sub-types, and biomarkers of MS and related demyelinating diseases.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Observational model case control
Arm

Eligibility Criteria

Male or female participants of any age.

Inclusion Criteria: - age 18+ able to give informed consent or individuals younger than 18 with parental permission and able to give assent - willing to provide up to 110 ml (50 ml for < 18 years old) of blood via venipuncture - experienced at least one CNS demyelinating event characteristic of MS, TM, NMO, ADEM, or ON Exclusion Criteria: - history of blood borne pathogens - allogeneic bone marrow transplant - clinical or radiological evidence of stroke, meningitis, or other well characterized diseases of the nervous system (with the exception of MS, TM, NMO, ADEM, or ON). - weight less than 37 pounds

Additional Information

Official title Large-scale, Multi-disciplinary Sample and Data Repository for Multiple Sclerosis and Related Demyelinating Diseases
Principal investigator Benjamin Greenberg, M.D., M.H.S.
Trial information was received from ClinicalTrials.gov and was last updated in July 2016.
Information provided to ClinicalTrials.gov by Accelerated Cure Project for Multiple Sclerosis.