Overview

This trial is active, not recruiting.

Conditions heart failure, coronary disease, heart valve diseases, cardiomyopathies, left ventricular hypertrophy
Sponsor Hiroaki Shimokawa, MD, PhD
Start date October 2006
End date March 2019
Trial size 10000 participants
Trial identifier NCT00418041, 2006-115

Summary

Chronic Heart Failure Analysis and Registry in the Tohoku District 2 (CHART-2 Study) is a large, prospective, hospital-based cohort study to investigate the following:

- Characteristics of patients with chronic heart failure and prognostic risks of these patients.

- Characteristics of patients with high risk for heart failure and critical factors which predict the development of symptomatic heart failure in these patients.

- The incidence and prognostic impact of metabolic syndrome in patients with chronic heart failure.

- The association between metabolic syndrome and the development of symptomatic heart failure.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Observational model cohort
Time perspective prospective

Primary Outcomes

Measure
All-cause death
time frame: At the time of registration and at least once a year thereafter
Non-fatal acute myocardial infarction
time frame: At the time of registration and at least once a year thereafter
Non-fatal stroke
time frame: At the time of registration and at least once a year thereafter
Heart failure requiring admission
time frame: At the time of registration and at least once a year thereafter

Eligibility Criteria

Male or female participants at least 20 years old.

Inclusion Criteria: - Structural heart disease but without signs or symptoms of heart failure. - Structural heart disease with prior or current symptoms of heart failure. - Refractory heart failure requiring specialized interventions. - Patients with prior cardiovascular surgery or percutaneous coronary intervention and those who need such interventions. Exclusion Criteria: - Patients with age<20 years old. - Patients who refused to participate.

Additional Information

Official title Chronic Heart Failure Analysis and Registry in the Tohoku District 2 (CHART-2 Study)
Description The CHART-2 Study is a multicenter prospective observational cohort study identifying the characteristics, mortality and prognostic risks of patients with overt HF and patients without HF but who are at high risk for disease progression of cardiovascular diseases (CVD). The purposes of the study are as follows: 1. to elucidate characteristics of patients with overt HF and the associated prognostic risks 2. to elucidate characteristics of patients at risk for HF and the factors associated with CVD progression 3. to elucidate factors associated with the development of AHFS 4. to elucidate prevalence and prognostic impact of metabolic syndrome (MetS) in patients with overt HF 5. to elucidate the association between MetS and the development of AHFS 6. to elucidate the prevalence and prognostic impact of malignancy in patients with CVD 7. to elucidate the prevalence of patients needing home nursing care and the characteristics of bedridden patients with CVD.
Trial information was received from ClinicalTrials.gov and was last updated in May 2015.
Information provided to ClinicalTrials.gov by Tohoku University.