Overview

This trial is active, not recruiting.

Condition proliferative vitreoretinopathy
Treatment low molecular weight heparin, 5-fu
Phase phase 3
Sponsor Shahid Beheshti Medical University
Start date February 2005
End date July 2007
Trial identifier NCT00371020, 8373

Summary

To evaluate the effect of combined 5-FU and low molecular weight heparin in infusion on the rate of retinal redetachment after silicone oil removal in cases of proliferative vitreoretinopathy (PVR).

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Allocation randomized
Endpoint classification safety/efficacy study
Intervention model parallel assignment
Masking double-blind
Primary purpose treatment

Primary Outcomes

Measure
Retinal redetachment rate
time frame:

Secondary Outcomes

Measure
visual acuity
time frame:
intraocular pressure
time frame:
reoperation
time frame:
relative afferent pupillary defect
time frame:

Eligibility Criteria

Male participants at least 18 years old.

Inclusion Criteria: - Cases with history of vitrectomy and silicone oil injection for management of PVR who undergo silicone oil removal Exclusion Criteria: - any sign of retinal redetachment before silicone oil removal - any sign of diabetic retinopathy

Additional Information

Principal investigator Hamid Ahmadieh, MD
Trial information was received from ClinicalTrials.gov and was last updated in July 2007.
Information provided to ClinicalTrials.gov by Shahid Beheshti Medical University.