Overview

This trial is active, not recruiting.

Conditions kidney stone, ureteroscopy
Treatment isoproterenol
Phase phase 2
Sponsor Fredericia Hosptial
Start date June 2006
End date February 2007
Trial size 10 participants
Trial identifier NCT00323843, 2005-005972-34

Summary

Is it possible to decrease the intrarenal pressure in the kidney during endoscopic management of kidney stone by topical administration of drugs? In order to secure fewer complications in ureteroscopic operations the pharmacological agent isoproterenol is tested on pigs and human to determine its potential of lowering intrarenal pressure.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Allocation non-randomized
Endpoint classification safety/efficacy study
Intervention model single group assignment
Masking open label
Primary purpose treatment

Primary Outcomes

Measure
Renal pelvic pressure
time frame:

Secondary Outcomes

Measure
Blood pressure
time frame:
Pulse
time frame:

Eligibility Criteria

Male or female participants at least 18 years old.

Inclusion Criteria: - Indication for RIRS procedure - Age > 18 years - Normotensive - Capable of understanding information given Exclusion Criteria: - Previous myocardiac infarct - Daily use of alpha- og beta- blocking medicine og calcium antagonists - Use of NSAID the last 2 days - Stone in the ureter - Declared - Known malignant disease in urinary tract - Bladder disease - Nephrostomies inserted - JJ-catheters inserted - Prisoners - Pregnant - Nursing mothers

Additional Information

Official title RIRS - A Method of Treating the ESWL Resistant Kidney Stone
Principal investigator Helene U Jung
Trial information was received from ClinicalTrials.gov and was last updated in January 2007.
Information provided to ClinicalTrials.gov by Fredericia Hosptial.