Overview

This trial is active, not recruiting.

Condition lung transplant recipients
Treatment celsior cold storage solution
Phase phase 3
Sponsor Johns Hopkins University
Start date December 2000
End date September 2005
Trial identifier NCT00284726, 00-10-25-03

Summary

The purpose of this study is to compare 2 different cold storage solutions, used to preserve donor lungs for lung transplantation, and their effect on cytokine activation related to ischemic reperfusion injury. Primary endpoint is 30 day survival.

United States No locations recruiting
Other Countries No locations recruiting

Eligibility Criteria

Male or female participants of any age.

Inclusion Criteria: Any patient undergoing a lung trasnplant at Johns Hopkins Hospital - Exclusion Criteria: -

Additional Information

Official title A Prospective, Controlled, Randomized Study on the Effect of Cold Storage Solutions on Complement Activation and Other Mediators of Ischemic Injury in Lung Transplantation
Principal investigator John V. Conte, M.D.
Description The length of ischemic time in harvesting lung allografts is associated with graft survival. It is further thought that ischemic changes in early post-transplantation bronchoscopic biopsies has a direct correlation with later development of chronic rejection.
Trial information was received from ClinicalTrials.gov and was last updated in January 2006.
Information provided to ClinicalTrials.gov by Johns Hopkins University.