Cortical Reorganisation in Patients With Primary Headache Disorders
This trial is active, not recruiting.
|Conditions||migraine without aura, chronic tension-type headache|
|Sponsor||Danish Headache Center|
|Trial identifier||NCT00263991, KA 05085|
Primary headache disorders are now accepted as physiological diseases, and advanced imaging-techniques have demonstrated a migraine generator in the brain stem and increased stimulus sensitivity in these patients. The underlying neuronal dysfunctions remain to to clarified and the existing neurophysiological methods have not yet been useful. More sensitive and reliable methods are therefore highly needed. The aims of the study are therefore to develop a sensitive and reliable method to demonstrate a cortical reorganisation and expansion of pain sensitive cortical areas in patients with migraine or tension-type headache.
|United States||No locations recruiting|
|Other countries||No locations recruiting|
|Observational model||case control|
Male or female participants from 18 years up to 65 years old.
- Clinical diagnosis og migraine without aura or chronic tension-type headache
- serious somatic or psychiatric diseases including depression
- overuse of analgesics
- regular intake of opiates or benzodiazepines
- intake of prophylactic headache medication
|Official title||Cortical Reorganisation in Patients With Primary Headache Disorders|
|Principal investigator||Lars Bendtsen, MD, Ph.d|
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