This trial is active, not recruiting.

Conditions cervix, cancer
Treatment colposcopy, spectroscopy, and biopsy
Sponsor University of New Mexico
Start date April 2004
End date December 2007
Trial size 100 participants
Trial identifier NCT00250055, 1104C


In general, to determine the sensitivity of light transport to tissue from morphological features of clinical significance.

Determine how specific structural features contribute to light scattering. Investigate light scattering differences in tumorigenic and nontumorigenic cells.

Develop and implement quantitative and sensitive methods for measuring morphological properties.

Clinical measurements.

United States No locations recruiting
Other countries No locations recruiting

Study Design

Allocation non-randomized
Intervention model single group assignment
Masking open label
Primary purpose diagnostic

Primary Outcomes

The objective of this study is to determine whether non-invasive measurements of light transport through tissue can identify pre-cancerous and cancerous conditions.
time frame: 6 years

Eligibility Criteria

Female participants at least 18 years old.

Inclusion Criteria: - Patients with abnormal Pap smears who are referred for colposcopy. Exclusion criteria include: - Anyone of the male sex since this study focuses on cervical cell abnormalities - Any woman who has had a hysterectomy, LEEP, or chemotherapy.

Additional Information

Official title Non-Invasive, Real-time Technology for Diagnosis of Cervical Tissue
Principal investigator Harriet Smith, MD
Description Patients undergoing a colposcopy will also have spectroscopy measurements taken and an extra biopsy of suspicious tissue.
Trial information was received from ClinicalTrials.gov and was last updated in March 2010.
Information provided to ClinicalTrials.gov by University of New Mexico.