This trial has been completed.

Condition depressive disorder, major
Sponsor University of California, Los Angeles
Start date January 2002
End date January 2011
Trial size 200 participants
Trial identifier NCT00229463, 01-10-049


The purpose of this study is to identify genes involved in depression. Specifically, the investigators will analyze some genes that may be related to whether or not a person responds to antidepressant medication. This project is part of basic scientific research to increase understanding of the role of genetic influences in psychological and mental processes involved in the response to treatment for depression.

United States No locations recruiting
Other countries No locations recruiting

Study Design

Observational model case control
Time perspective cross-sectional

Eligibility Criteria

Male or female participants from 18 years up to 75 years old.

Inclusion Criteria: - History of Unipolar Major Depression - Control subjects must be healthy normal adults Exclusion Criteria: - Subjects with mood symptoms that are not severe enough to qualify for MDD - Subjects with any active medical illness that may be related to ongoing mood disorder - Normal subjects must be free from: a psychiatric diagnosis, substance abuse, a history of seizure disorder, and any serious medical illness

Additional Information

Official title Study of Genetic Differences in People With Depression
Principal investigator Andrew F. Leuchter, M.D.
Trial information was received from ClinicalTrials.gov and was last updated in November 2016.
Information provided to ClinicalTrials.gov by University of California, Los Angeles.