Stress, Diurnal Cortisol, and Breast Cancer Survival
This trial is active, not recruiting.
|Collaborator||National Institute on Aging (NIA)|
|Start date||September 2002|
|End date||November 2004|
|Trial size||115 participants|
|Trial identifier||NCT00226967, 12273, 76389, BRSADJ0006|
The purpose of this study is to learn about the effects of stress on hormones, the relationship between these hormones and cancer progression.
Female participants at least 35 years old.
- Diagnosis of recurrent or metastatic breast cancer.
- Karnofsky of 70% or greater.
- Proficient enough in English to be able to take questionnaires and participate in the required tasks.
- Living within the Greater Bay Area.
- Age 35 or older .
- Positive supraclavicular lymph nodes as the only metastatic lesion at the time of initial diagnosis.
- Active cancers within the past 10 years other than breast cancer, basal cell or squamous cell carcinomas of the skin, or in situ cancer of the cervix.
- Any other serious medical condition that will effect short term survival
- History of major psychiatric illness for which patient was hospitalized or medicated, with the exception of depression or anxiety
- A diagnosis of diabetes.
|Official title||Stress, Diurnal Cortisol, and Breast Cancer Survival|
|Principal investigator||David Spiegel|
|Description||The purpose of this study is to investigate stress and tonic activation of diurnal cortisol in aging metastatic breast cancer patients; feedback inhibition & activation of cortisol; and stress-induced phasic activation of cortisol.|
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