This trial is active, not recruiting.

Conditions obesity, osteoarthritis
Treatment gastric bypass surgery
Sponsor University Hospitals of Cleveland
Collaborator Elizabeth Severance Prentiss Foundation
Start date February 2003
End date May 2006
Trial size 35 participants
Trial identifier NCT00194051, 02-03-10


Weight is a risk factor for knee osteoarthritis

Knee osteoarthritis is associated with abnormal gait biomechanics

Gait biomechanics are evaluated in gastric bypass patients before and after losing 100 pounds.

United States No locations recruiting
Other countries No locations recruiting

Study Design

Observational model defined population
Time perspective longitudinal

Eligibility Criteria

Male or female participants from 35 years up to 60 years old.

Inclusion Criteria: Undergoing gastric bypass surgery At least 35 years old - Exclusion Criteria: Inability to walk unassisted Pain affecting gait in any lower extremity joint -

Additional Information

Official title Symptomatic, Biomechanical and Radiographic Outcomes in Knee Osteoarthritis Following Gastric Bypass Surgery
Principal investigator Michele M Hooper, MD, MS
Description Weight is a major risk factor for development of knee osteoarthritis, but not hip or ankle arthritis. One possible mechanism for this is the generation of abnormal gait biomechanics secondary to obesity that are conducive to the development of knee osteoarthritis. We evaluate gait biomechanics, knee symptoms and knee radiographs in 35 obese patients before and after gastric bypass surgery to determine the effect of significant weight loss on gait biomechanics, knee symptoms and knee radiographs.
Trial information was received from ClinicalTrials.gov and was last updated in October 2006.
Information provided to ClinicalTrials.gov by University Hospitals of Cleveland.