This trial is active, not recruiting.

Condition stress disorders, post-traumatic
Treatment prazosin
Sponsor Rainier Associates
Start date November 2003
End date November 2005
Trial size 20 participants
Trial identifier NCT00174551, 20031050


Investigating the effect of prazosin for nighttime symptoms of civilian Posttraumatic Stress Disorder.

United States No locations recruiting
Other countries No locations recruiting

Study Design

Allocation randomized
Endpoint classification efficacy study
Intervention model crossover assignment
Masking double-blind
Primary purpose treatment

Primary Outcomes

Sleep time
time frame:
REM sleep time
time frame:
Nightmare frequency
time frame:
time frame:

Secondary Outcomes

Distressed Awakenings frequency
time frame:
time frame:

Eligibility Criteria

Male or female participants from 18 years up to 80 years old.

Inclusion Criteria: - must meet DSM-IV criterion for PTSD Exclusion Criteria: - Must not have untreated sleep apnea

Additional Information

Official title The Effect of Prazosin for Nighttime Symptoms of Civilian PTSD
Principal investigator Fletcher B Taylor, M.D.
Description Each subject will receive prazosin and placebo trials, the order randomized. Day and nighttime symptoms will be monitored.
Trial information was received from ClinicalTrials.gov and was last updated in September 2006.
Information provided to ClinicalTrials.gov by Rainier Associates.