This trial is active, not recruiting.

Conditions alcohol-related disorders, cocaine-related disorders
Treatment disulfiram
Phase phase 1
Sponsor National Institute on Drug Abuse (NIDA)
Start date August 2004
End date July 2005
Trial size 16 participants
Trial identifier NCT00094289, NIDA-MDS-0003-1


The purpose of this study is to assess potential interactions between intravenous cocaine and ethanol and oral disulfiram.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Primary purpose treatment

Primary Outcomes

Safety assessments
time frame:
Psychological effects
time frame:

Eligibility Criteria

Male or female participants from 18 years up to 50 years old.

Inclusion Criteria: - Must meet DSM-4 criteria for cocaine abuse or dependence and are not seeking treatment. - Ability to verbalize understanding of consent form and provide written informed consent and verbalize willingness to complete study procedures; be able to comply with protocol requirements. Exclusion Criteria: - Please contact site for more information.

Additional Information

Official title Interactions Between IV Cocaine and Ethanol and Oral Disulfiram
Principal investigator John Roache, Ph.D.
Description This is a two-site, double blind, placebo-controlled inpatient study to determine the cardiovascular and psychiatric safety of alcohol use in cocaine-dependent subjects who had used cocaine after treatment with disulfiram.
Trial information was received from ClinicalTrials.gov and was last updated in October 2007.
Information provided to ClinicalTrials.gov by National Institute on Drug Abuse (NIDA).