Drug Interaction Study With NS2359 and Cocaine in Cocaine Experienced Volunteers - 1
This trial is active, not recruiting.
|Conditions||cocaine-related disorders, drug administration schedule, infusions, intravenous|
|Sponsor||National Institute on Drug Abuse (NIDA)|
|Start date||June 2001|
|End date||December 2002|
|Trial size||24 participants|
|Trial identifier||NCT00032916, NCT00031330, NIDA-CPU-2359-02-1|
The purpose of this study is to conduct a drug interaction study with NS2359 and cocaine in cocaine experienced volunteers.
Pharmacokinetic parameter comparison
Male or female participants from 18 years up to 45 years old.
Inclusion Criteria: Male or Female, 18-45 yrs of age; females of child-bearing potential using appropriate method of birth control; be able to understand the procedure and agrees to participate via informed consent; must be cocaine dependent according to DSM-4 criteria; must be capable of providing written consent; must be able to comply with protocol requirement, CPU rules and regulations; must not be currently seeking treatment for cocaine abuse. Exclusion Criteria: Incapable of understanding the informed consent process; Additional criteria available during screening at the site.
|Official title||Drug Interaction Study With NS2359 and Cocaine in Cocaine Experienced Volunteers|
|Principal investigator||Louis Cantilena, M.D.|
|Description||This is a single-center, double-blind, placebo-controlled, randomized, single dose, fixed order, dose escalating inpatient design that will study oral NS2359 in cocaine experienced volunteers.|
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