NF2 Natural History Consortium
This trial is active, not recruiting.
|Conditions||schwannoma, vestibular, neurofibromatosis 2, meningioma|
|Sponsor||House Ear Institute|
|Start date||January 2002|
|Trial size||100 participants|
|Trial identifier||NCT00004483, 199/14226, HEI-DAMD17-01-1-0710, HEI-NF2|
I. Define the growth rates and clinical course of NF2-related tumors in patients with neurofibromatosis type 2. Associate growth rate with physical function.
|Observational model||natural history|
Male or female participants at least 5 years old.
PROTOCOL ENTRY CRITERIA: --Disease Characteristics-- - Diagnosed with neurofibromatosis 2 on or after 01/01/93 - Must meet one of the following conditions: Bilateral vestibular schwannoma OR Family history of neurofibromatosis 2 (first degree family relative) AND Unilateral vestibular schwannoma at under 30 years OR Any 2 of the following: Meningioma Glioma Schwannoma Juvenile posterior subcapsular lenticular opacity/juvenile cortical cataract - No plans to treat vestibular schwannoma in next 12 months --Prior/Concurrent Therapy-- - Not specified --Patient Characteristics-- - Age: 5 and over
|Description||PROTOCOL OUTLINE: Data on the clinical course and growth rate of NF2-related tumors in patients with neurofibromatosis 2. Patients are evaluated each year on a cranial and a spinal MRI, eye tests, hearing tests, quality of life, neurological tests, and physical functioning.|
Call for more information