Overview

This trial is active, not recruiting.

Conditions cocaine-related disorders, opioid-related disorders, substance-related disorders
Treatment buprenorphine
Phase phase 3
Sponsor National Institute on Drug Abuse (NIDA)
Collaborator Yale University
Start date September 1999
Trial size 168 participants
Trial identifier NCT00000311, NIDA-09413-1, R01-09413-1

Summary

The purpose of this study is to evaluate whether the community reinforcement approach (CRA) plus contingency management (CM) is more effective overall than CRA only in reducing illicit opioid and cocaine use during agonist maintenance treatment and at 3 and 6 month follow-up after completion of study protocol, and to compare the efficacy of maintenance on buprenorphine to methadone when maintenance is combined with CRA only or CRA plus CM.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Primary purpose treatment
Arm
(Experimental)
Therapeutic Contracting (TC)
buprenorphine
Experimental Therapeutic Contracting (TC) Experimental Cognitive Behavioral Coping Skills Therapy (CBT)
(Experimental)
Cognitive Behavioral Coping Skills Therapy (CBT)
buprenorphine
Experimental Therapeutic Contracting (TC) Experimental Cognitive Behavioral Coping Skills Therapy (CBT)

Primary Outcomes

Measure
Depression
time frame:
Withdrawal symptoms
time frame:
Opioid and cocaine use
time frame:
Social and psychological functioning
time frame:
AIDS risk behavior
time frame:

Eligibility Criteria

Male or female participants of any age.

Please contact site for information.

Additional Information

Official title Combining Behavioral Treatment With Agonist Maintenance
Principal investigator Richard Schottenfeld, M.D.
Trial information was received from ClinicalTrials.gov and was last updated in October 2008.
Information provided to ClinicalTrials.gov by National Institute on Drug Abuse (NIDA).